Dr. Whitaker

Contrary to popular belief, the leading liver problem in the United States is not alcoholic cirrhosis or hepatitis, but nonalcoholic fatty liver disease (NAFLD). Afflicting roughly one in four Americans, it is not caused by alcohol or a virus, but by obesity and insulin resistance—and at least half of all people with type 2 diabetes are affected.

NAFLD is a progressive disease with three distinct stages. Simple fatty liver, or steatosis, is characterized by elevations in liver enzymes and fatty deposits in the liver (at least 10 percent of the liver cells are replaced by fat). If the disease is arrested in this stage, it remains relatively benign. Unfortunately, for one in five patients, it progresses to nonalcoholic steatohepatitis, involving inflammation of the liver. From there, half develop cirrhosis, marked by advanced and irreversible scarring, fibrosis, and loss of liver function.

Why am I telling you this? Because the most significant risk factors for progression include type 2 diabetes and metabolic syndrome (syndrome X).

To treat or protect against this condition, I recommend regular supplementation with nutrients that enhance liver function (particularly detoxification) in addition to supplements for diabetes. Look for the following products—as stand-alone products or in combination formulas—in your health food store: lipoic acid, 100 mg; silymarin, 420 mg; selenium, 70 mcg; calcium-D-glucarate, 200 mg; N-acetylcysteine, 600 mg; ellagic acid, 50 mg; and trimethylglycine, 300 mg.