When blood glucose levels remain elevated for an extended period of time, sticky sugar molecules can attach to protein molecules in a process called glycation. Glycation of protein molecules creates irreversible cross-links between adjacent protein molecules. This cross-linking creates new protein structures called AGEs (Advanced Glycosylation End products).
If you’re dealing with diabetes, you’ll want to be particularly aware of this because, among other things, AGEs can cause tissues like the collagen in your blood vessels to become stiff and lose their flexibility. This is a major culprit behind many diabetic complications, including cataracts and diabetic retinopathy.
But, the good news is that there are two supplements for diabetes that are especially good for your eyes.
- Grape Seed Extract. Grape seed extract is a powerful antioxidant that protects blood vessels and capillaries from free-radical damage. Research shows that grape seed extract can also help prevent diabetic retinopathy. The initial dose is one mg per pound of body weight for the first week, in divided doses with meals, continuing with a maintenance dose of one-half this amount. Round your weight up or down to the nearest 50 pounds. For example, if you weigh 210 pounds, take 200 mg a day for the first week, and then continue on 100 mg a day.
- Benfotiamine. According to researchers at Case Western Reserve University in Cleveland, Ohio, benfotiamine blocks three of the major culprits responsible for blood vessel damage in patients with elevated blood sugar levels. As a result, it helps prevent retinopathy, neuropathy, and other diabetes complications.
Although benfotiamine is found in small quantities in garlic, shallots, leeks, and onions, you’d have to eat an awful lot of these vegetables to obtain therapeutic doses. If you want to forego the bad breath, I suggest you use benfotiamine in capsule form. Look for it in your local health food store. Typical doses range from 150 to 450 mg daily.
Diabetes, like most chronic illnesses, is often (and rightly) characterized as a disease of lifestyle. Specific lifestyle choices can create and exacerbate type 2 diabetes, but as Dr. Whitaker has proven time and again, the right lifestyle changes can prevent, treat and even reverse type 2 diabetes as well.
But do some people have the cards stacked against them, where developing diabetes is an inevitable component of their very genetic makeup? To read the latest study in Nature Genetics, you might reach that conclusion.
There's no disputing that there is a strong, inheritable correlation present with type 2 diabetes. If your mother, father, sister or brother has it, your risk of developing diabetes goes up considerably. Your identical twin has diabetes? Your risk is even higher.
Now researchers have identified 10 new genetic variants that lead to differences in glucose levels for non-diabetic people. Half of these genetic differences also correlate to the risk of developing type 2 diabetes.
"Finding these new pathways can help us better understand how glucose is regulated, distinguish between normal and pathological glucose variations and develop potential new therapies for type 2 diabetes," Dr Jose Florez, one of the lead researchers, explained.
What researchers go on to say is that by studying healthy people without type 2 diabetes, their hope is we can better understand how to treat those people who are currently living with diabetes, or those simply trying to manage blood sugar every day.
No dispute here, it's an admirable pursuit. And most experts concede that the future of medicine will be greatly influenced by the study of the human genome. But a danger few people talk about is this science of medicine instead fueling a belief that if you have a genetic predisposition towards a disease, all you're left to do is throw up your hands and live with it.
The fact is, 55 percent of people dealing with type 2 diabetes are struggling with their weight, and regardless of your genes, diabetes and weight are unquestionably connected.
Another lifestyle correlation -- making regular exercise a part of your life -- dramatically impacts your likelihood of facing type 2 diabetes, now or in the future.
By understanding how to manage your risk -- with the proper diet that promotes insulin sensitivity, with supplements for diabetes that make maintaining blood sugar safe and manageable -- you gain control of your genes, not allow your genes to seal your fate.
The fact that you're reading this means you're already taking steps to understand your role in your own health.
Remember, as Dr. Whitaker says, you're in charge. Not your doctor. Not the system. And, as we'll have to keep in mind as more studies like this come out, not your genes.
Contrary to popular belief, the leading liver problem in the United States is not alcoholic cirrhosis or hepatitis, but nonalcoholic fatty liver disease (NAFLD). Afflicting roughly one in four Americans, it is not caused by alcohol or a virus, but by obesity and insulin resistance—and at least half of all people with type 2 diabetes are affected.
NAFLD is a progressive disease with three distinct stages. Simple fatty liver, or steatosis, is characterized by elevations in liver enzymes and fatty deposits in the liver (at least 10 percent of the liver cells are replaced by fat). If the disease is arrested in this stage, it remains relatively benign. Unfortunately, for one in five patients, it progresses to nonalcoholic steatohepatitis, involving inflammation of the liver. From there, half develop cirrhosis, marked by advanced and irreversible scarring, fibrosis, and loss of liver function.
Why am I telling you this? Because the most significant risk factors for progression include type 2 diabetes and metabolic syndrome (syndrome X).
To treat or protect against this condition, I recommend regular supplementation with nutrients that enhance liver function (particularly detoxification) in addition to supplements for diabetes. Look for the following products—as stand-alone products or in combination formulas—in your health food store: lipoic acid, 100 mg; silymarin, 420 mg; selenium, 70 mcg; calcium-D-glucarate, 200 mg; N-acetylcysteine, 600 mg; ellagic acid, 50 mg; and trimethylglycine, 300 mg.
As I’ve said many times (and conventional medicine continues to ignore) diabetes is a nutritional wasting disease. As a result of the continual nutritional losses that occur in people with diabetes, body parts simply fall off.
Diabetes is our number-one cause of blindness, amputation, and kidney failure. It dramatically increases the risk of both heart attack and stroke. And if you have pre-diabetes or metabolic syndrome (also called syndrome X), you’re on the road to significant complications if you don’t address these nutrient losses with high-dose, targeted supplements for diabetes.
Folks, it’s not complicated. If you were to give a healthy person an osmotic diuretic every day and did not replace nutrients, you would produce the same complications suffered by those living with diabetes and related conditions.
Let’s examine some of these losses and what they mean for you.
Magnesium. Excessive urination washes out magnesium. Low magnesium levels are present in 25 percent of those with diabetes, and even those with levels considered to be “high” don’t reach the average levels of those without blood sugar concerns.
Magnesium is involved in glucose transfer across cell membranes and improves insulin sensitivity and glucose control. When magnesium goes down, glucose control deteriorates. That’s because magnesium is essential to normal carbohydrate metabolism.
Low magnesium levels are associated with the diabetic retinopathy. Said another way, if you have diabetes and you have very low magnesium, you are at the greatest risk of going blind. Low magnesium levels are also connected to high blood pressure and heart disease. Now, shouldn’t everyone living with diabetes be taking magnesium supplements to reduce or completely avoid such devastating complications?
Zinc is another water-soluble nutrient that is flushed from the body, and as a result, diabetes produces low zinc levels. This complication can impair the immune system, particularly T-cell function, which could lead to more infections and non-healing ulcers. Zinc deficiency also can cause hair loss as well as diarrhea, which triggers further nutrient losses still. All together now, shouldn’t everyone with diabetes be taking zinc supplements?
B-complex vitamins. B6, B12, and folic acid are also water-soluble and vulnerable to loss via excessive urination from diabetes. This leads to increased homocysteine levels and dramatically increased risk of heart disease.
Low levels of B6 can cause glucose intolerance, depression, cracked lips, and dry skin. A B12 deficiency may exhibit no obvious symptoms at first, but over time can produce mental disturbances, anemia, and impaired nerve function. A lack of folic acid may bring on depression, forgetfulness, insomnia, irritability, and fatigue. Repeat after me. Shouldn’t everyone living with diabetes be taking supplemental B vitamins?
Diabetes complications are as frightening as the disease itself--which is growing exponentially in this country. Given these facts, you’d think the most basic aspects of this illness would at least be understood, if not one of the primary focuses of treatment. Sadly, this isn’t happening.
It’s up to us. I’ll keep spreading the word. And if you have diabetes, you owe it to yourself to get on a high-dose supplement program as soon as possible, with a particular emphasis on these water soluble nutrients.
As General Manager of Forward Nutrition, I get a lot of questions about supplements. These days, many of you are asking what Dr. Whitaker recommends when facing a significant health concern like diabetes.
Are there specific supplements he has recommended for years? Are there supplements Dr. Whitaker has had success using with patients to manage blood sugar naturally? Are there different supplements to control blood sugar, target Syndrome X, manage pre-diabetes or beat type 2 diabetes? What about weight loss -- does Dr. Whitaker have suggestions for that?
The short answer (and that's what blogs are for,
short answers) is yes, there are many different supplements for diabetes and related blood sugar concerns. Over the next few posts, I'll focus on Dr. Whitaker's favorites, the tried-and-true, and as new ones come along, you'll be sure to hear about them here.
Vanadium: A Cornerstone of the Whitaker Wellness Approach
According to Dr. Whitaker, one of the most effective and intriguing nutritional supplements for managing blood sugar levels is vanadium. This trace mineral lowers blood sugar by mimicking insulin and improving the cells’ sensitivity to insulin. Studies show that supplementation with vanadium (as vanadyl sulfate) markedly lowers fasting glucose and improves other measures of diabetes.
In one study, eight people with type 2 diabetes who received 50 mg of vanadyl sulfate twice a day for four weeks were found to have a 20 percent reduction in average fasting blood sugar, which lasted well after the mineral was discontinued. The only reported adverse effect was minor gastrointestinal distress during the first few days of the study.
Dr. Whitaker's suggested dose of vanadyl sulfate is 30 mg daily. If you need extra support and are under a doctor’s care, you can take up to 100 mg per day.
Pretty powerful stuff. And that's just one of many solutions. Look for more specific recommendations in upcoming posts, and keep the questions coming!
As the General Manager of Forward Nutrition, I'm constantly reading and researching about supplements and health, particularly when it involves diabetes. Diabetes and Metabolic Syndrome are huge problems that are only getting worse in this country, and natural treatments for diabetes don't get nearly the attention they deserve.
This article from the April 2009 issue of Nutritional Outlook (ok, I'm a little behind) is too good not to share.
Entitled "Understanding a Silent Killer," this is must reading if you're at all concerned about diabetes, maintaining or managing blood sugar, or seeking natural, safe treatments to treat Type 2 diabetes.
Among the natural treatments for diabetes care discussed are alpha-lipoic acid, dietary fiber, gymnema sylvestre and chromium. These nutrients have been shown repeatedly to help manage blood sugar, control blood sugar spikes, and reduce sugar cravings and mood swings.
Alpha-lipoic acid doesn't just improve insulin sensitivity, but also protects against diabetic complications like peripheral nerve pain. It's one of the best natural diabetes treatments, and it also helps your body utilize the other antioxidants you take, like vitamins C and E.
Powered by Compendium Blogware